Allergy as a Trigger and Consequence
- Mechanism:
- Allergies are hypersensitive immune responses to environmental allergens (e.g., pollen, dust).
- Histamine release and inflammatory mediator production aggravate inflammation.
- Impact on Other Conditions:
- Inflammation: Allergic reactions drive localized inflammation (e.g., in the airways or skin) and systemic immune activation.
- Stress: Persistent allergic symptoms lead to emotional and physical stress, exacerbating the cycle.
- Oxidative Stress: Allergies increase oxidative stress by activating immune cells that release ROS during inflammation.