Depression: A Downstream Effect
- Mechanism:
- Chronic inflammation, oxidative stress, and stress contribute to neuroinflammation and neurotransmitter imbalance, which can lead to depression.
- Depression can also worsen stress and inflammation, creating a self-perpetuating cycle.
- Impact on Other Conditions:
- Stress: Depression heightens the perception of stress, increasing cortisol production.
- Oxidative Stress: Depressive states are linked to reduced antioxidant levels and increased oxidative damage.
- Inflammation: Depressed individuals often show elevated inflammatory markers, linking mood disorders to systemic inflammation.